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The Science Behind Inhaled Therapeutics

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Genetic sequences engineered to produce vaccine antigens of interest are inserted into the adenoviral DNA.

The antigens produced by these genetic sequences will trigger an immune response after inoculation.

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HOW IT WORKS 

Recombinant Adenovirus Vectored Vaccines

Adenoviruses are naturally adept at targeting the respiratory epithelium and are readily modified to express vaccine antigens of interest. With demonstrated safety in human clinical trials for Mycobacterium tuberculosis and SARS-CoV-2, these vectors offer a promising platform for inhaled vaccine delivery.

PRECISION DELIVERY

Aerogen Solo Nebulizer

The Aerogen Solo Nebulizer is a state-of-the-art drug delivery system that uses a vibrating mesh aperture plate to aerosolize liquid vaccines into fine droplets, less than 5 microns in size. ​

​These tiny droplets are perfectly suited for efficient deposition into the major airways, optimizing the delivery of inhaled vaccines. 

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INJECTABLE VACCINES

Primarily stimulate systemic immunity but often fail to target mucosal immunity effectively, leading to incomplete protection against respiratory pathogens.

INHALED VACCINES

Inhalation bypasses barriers associated with injectables, such as poor mucosal targeting and systemic clearance, stimulating both mucosal and systemic immunity while being non-invasive

DIRECT-TO-LUNG IMMUNITY

Inhaled Vaccines

Explore a new era in vaccination: our needle-free delivery targets immune responses directly in the airways, offering enhanced protection with ease and comfort.

MULTI-LAYERED IMMUNE PROTECTION

Eliciting Broad Immunity

Many pathogens have evolved ways to evade our immune defenses. Our approach incorporates multiple antigens into each vaccine,  offering multiple immune barriers to preserve our health and well-being.

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ANTIBODIES

T CELLS

TRAINED IMMUNITY

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© 2024 AeroImmune Inc. 

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